Fig. 4.

EKODE increases DSS-induced colitis in mice. A, Scheme of animal experiment. The dose of EKODE is 1 mg/kg/day, administered via intraperitoneal injection. B, H&E staining of colon (n = 6 mice per group, scale bars: 50 μm). C, Gene expression of Tnf-α, Jun, Myc and Mki67 in colon (n = 4–7 mice per group). D, FACS quantification of immune cells in colon (n = 5–7 mice per group). The results are mean ± SEM. The statistical significance of two groups was determined using Student's t-test or Wilcoxon-Mann-Whitney test.