EKODE induces intestinal barrier dysfunction and increases LPS/bacterial translocation. A, LPS concentration in plasma (n = 6–8 mice per group). B, Gene expression of 16S rRNA gene in blood and spleen (n = 4–6 mice per group). C, Gene expression of Il-1β, Tnf-α and Il-10 in spleen (n = 4–7 mice per group). D, Gene expression of Occludin in colon (n = 5–7 mice per group). E, IHC staining of Occludin in colon (n = 6–7 mice per group, scale bars: 50 μm). The results are mean ± SEM. The statistical significance of two groups was determined using Student's t-test or Wilcoxon-Mann-Whitney test.