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Immune cell-produced ROS and its effects on tumor progression. Red arrows indicate pro-tumorigenic, green arrows tumor-suppressive effects of immune cell-derived ROS. Abbreviations: DC = Dendritic cell, MDSC = Myeloid-derived suppressor cell, NET = Neutrophil extracellular trap, NK cell = Natural killer cells, TAM = Tumor-associated macrophage. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)
