Table 4.
Correlation Coefficients Between Cholesteryl Esters and Rosiglitazone
| Cholesteryl Ester (CE) | Correlation Coefficient (ρ) | Significance (p-value) | Cholesteryl Ester (CE) | Correlation Coefficient (ρ) | Significance (p-value) |
|---|---|---|---|---|---|
| CE 14:0 | 0.127 | 0.389 | CE 22:6 | −0.094 | 0.525 |
| CE 15:0 | −0.230 | 0.116 | CE 22:5 | −0.089 | 0.549 |
| CE 16:2 | −0.469 | 0.001 | CE 22:4 | −0.209 | 0.154 |
| CE 16:1 | 0.273 | 0.061 | CE 22:3 | −0.077 | 0.602 |
| CE 16:0 | 0.337 | 0.019 | CE 22:2 | −0.086 | 0.561 |
| CE 17:1 | −0.011 | 0.941 | CE 22:1 | 0.500 | <0.001 |
| CE 17:0 | −0.063 | 0.670 | CE 24:2 | 0.227 | 0.122 |
| CE 18:3 | −0.011 | 0.940 | CE 24:1 | 0.698 | <0.001 |
| CE 18:2 | −0.041 | 0.785 | CE 24:0 | 0.453 | 0.001 |
| CE 18:1 | −0.589 | <0.001 | CE 26:2 | 0.168 | 0.253 |
| CE 18:0 | 0.426 | 0.003 | CE 26:1 | 0.656 | <0.001 |
| CE 19:1 | −0.187 | 0.203 | CE 26:0 | 0.130 | 0.378 |
| CE 20:5 | −0.295 | 0.042 | CE 27:3 | 0.026 | 0.862 |
| CE 20:4 | 0.133 | 0.369 | CE 28:1 | 0.694 | <0.001 |
| CE 20:3 | −0.300 | 0.038 | CE 30:1 | 0.245 | 0.093 |
| CE 20:2 | −0.346 | 0.016 | CE 32:1 | −0.085 | 0.566 |
| CE 20:1 | −0.022 | 0.881 | CE 34:1 | −0.384 | 0.007 |
Spearman’s correlation coefficients were calculated between each cholesteryl ester (CE) and rosiglitazone. CEs are listed with two numbers. The two numbers denote the number of carbons and double bonds in the acyl chains, respectively. All correlations are positive unless otherwise denoted. Thirteen CEs (bolded) reached statistical significance. Five of these CEs had moderate to high correlations: CE 24:1, CE 28:1, CE 26:1, CE 18:1, and CE 22:1. n = 48 for each CE.