Table 3.
Characteristics of stem cell boost population (n = 10, including one patient who required two stem cell boosts)
Characteristic | Median (range) | ||
---|---|---|---|
Age, years | 62 (47–72) | ||
Response status prior to first ASCT | SD | 1 | |
PR | 5 | ||
CR/VGPR | 4 | ||
CD34+ dose at ASCT (x 106/kg) | 3.1 (1.8–18) | ||
Day of stem cell boost after ASCT | 35 (17–81) | ||
Stem cell boost dose (CD34+ cells × 106/kg) | 5.6 (1.9–20) | ||
Day of engraftment following stem cell boost | Neutrophil | 4 (2–11) | |
Hemoglobin | 15 (4–34) | ||
Platelet | 12 (0–34) | ||
Number of patients | |||
Indication for boost | Delayed engraftment | 6 | |
Non-engraftment | 4 (including 1 patient who required second boost for delayed engraftment) | ||
New pancytopenia | 1 |
Table abbreviations: ASCT = autologous stem cell transplant; SD = stable disease, VGPR = very good partial response; PR = partial response; CR = complete response; PD = progressive disease