Table 1.
Baseline participant demographics, and recruitment CT characteristics
| Characteristic | Study population (n = 355) |
|---|---|
| Age, years | 67.9 ± 9.0 |
| Sex, female | 171 (48%) |
| Smoking status | |
| Current | 89 (25%) |
| Ex | 195 (55%) |
| Never | 60 (17%) |
| Respiratory PMH | |
| COPD | 123 (35%) |
| Asthma | 39 (11%) |
| Pulmonary fibrosis | 7 (2%) |
| TB | 10 (3%) |
| Inhalational exposures | |
| Asbestos | 62 (17%) |
| Coal | 14 (4%) |
| Silica | 4 (1%) |
| Prior malignancy | 46 (13%) |
| Recruitment CT characteristics | |
| Nodule location | |
| Right upper lobe | 102 (29%) |
| Right middle lobe | 23 (6%) |
| Right lower lob | 74 (21%) |
| Left upper lobe | 80 (23%) |
| Lingula | 15 (4%) |
| Left lower lobe | 61 (17%) |
| Size, mm | 15.8 ± 5.5 |
| CT grade | |
| 1 | 14 (4%) |
| 2 | 67 (19%) |
| 3 | 241 (68%) |
| Histology (malignant, n = 209) | |
| Non Small cell lung cancer | 147 |
| Adenocarcinoma | 112 |
| Squamous cell carcinoma | 31 |
| Large cell undifferentiated | 2 |
| Not otherwise specified | 2 |
| Carcinoid tumour | 11 |
| Small cell lung cancer | 4 |
| Radiological diagnosis only/SABR | 42 |
| Other | 5 |
COPD, chronic obstructive pulmonary disease; CT, computed tomography; PMH, past medical history; SABR, sterotactic ablative radiotherapy; TB, tuberculosis