Table 1.
Risk of T cell lymphopenia (TCL) or SCID Relative to NBS Profile
| NBS Profile | SCID Risk# | TCL Risk* | ||||
|---|---|---|---|---|---|---|
| NICU | Not NICU | All | NICU | Not NICU | All | |
| Undetectable TREC on Initial NBS | 0.05 (1/20) | 0.47 (7/15) | 0.22 (8/35) | 1.0 (14/14) | 0.93 (14/15) | 0.97 (28/29) |
| OOR but detectable TREC levels on two serial specimens in the absence of a normal result | 0.006 (1/156) | 0.0 (0/46) | 0.005 (1/202) | 0.84 (92/109) | 0.91 (42/46) | 0.86 (134/155) |
| Total | 0.01 2/176 | 0.11 (7/61) | 0.04 (9/237) | 0.86 (106/123) | 0.92 (56/61) | 0.88 (162/184) |
*
TCL Risk calculated using denominator of infants within a particular NBS profile who had flow cytometry testing completed with TCL defined as CD3 <2500
#
SCID Risk calculated using denominator of all infants within a particular NBS profile