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. 2020 Nov 21;48(6):1998–2008. doi: 10.1007/s00259-020-05092-3

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Kaplan-Meier survival curves for progression-free survival (PFS, left panels a–c) and overall survival (OS, right panels a–c) in responding (CMR, complete metabolic response or PMR, partial metabolic response) versus non-responding patients (SMD, stable metabolic disease or PMD, progressive metabolic disease) using SUL_max (EORTC PET response criteria) and SUL_peak (PERCIST). For metabolic active tumor volume (MATV) and total lesion glycolysis (TLG), the thresholds used to discriminate between responders and non-responders were the median values of the series (− 74.2% for MATV and − 78.3% for TLG). MATV and TLG being perfectly correlated, they produced similar results and only the Kaplan-Meier curves for MATV are displayed in panel d