Table 1.
Patient characteristics
| Training cohort | External validation cohort | |
|---|---|---|
| Center | Freiburg, Germany | Nanjing, China |
| Enrollment | Prospective | Retrospective |
| Histology | Whole-mount histopathology | Whole-mount histopathology |
| Patients (n) | 20 | 52 |
| Age in years (median, range) | 67 (48–76) | 69 (55–84) |
| ISUP (n) | ||
| 1 | 1 | 6 |
| 2 | 7 | 13 |
| 3 | 5 | 16 |
| 4 | 4 | 8 |
| 5 | 3 | 9 |
| pT stage (n) | ||
| 2 | 8 | 17 |
| 3a | 6 | 24 |
| 3b | 6 | 11 |
| 4 | 0 | 0 |
| Median iPSA (ng/ml) | 16.9 (5.6–218) | 13.5 (4.1–110) |
The patient characteristics of the different cohorts as well as the study design and histologic reference material are listed as an overview. Whole-mount histopathology is generated by radical prostatectomy
iPSA initial PSA