Table 3.
Diagnostic accuracy of [18F]FDG-PET/CT findings
| Site positive on [18F]FDG-PET/CT | No. of patients (no. of cohortsb) | Sensitivity (95% CI) | Specificity (95% CI) | Diagnostic OR (95% CI) | LR+ (95% CI) | LR− (95% CI) |
|---|---|---|---|---|---|---|
| Hip | 346 (5) | 63.7 (46.3–78.1) | 78.1 (69.1–85.1) | 6.25 (3.32–11.79) | 2.91 (2.09–4.05) | 0.47 (0.31–0.70) |
| Greater trochanter | 428 (6) | 83.3 (59.0–94.5) | 56.7 (38.3–73.5) | 6.54 (2.87–14.90) | 1.93 (1.43–2.59) | 0.29 (0.13–0.66) |
| Interspinous bursa | 546 (6) | 74.5 (59.3–85.4) | 81.4 (59.6–92.8) | 12.76 (5.64–28.89) | 4.00 (1.84–8.71) | 0.31 (0.21–0.47) |
| Ischial tuberosity | 428 (6) | 85.4 (62.3–95.4) | 70.1 (53.5–82.7) | 13.72 (5.20–36.18) | 2.86 (1.91–4.28) | 0.21 (0.08–0.54) |
| Shouldera | 406 (6) | 78.4 (65.4–87.5) | 69.5 (42.5–87.5) | 8.30 (3.05–22.58) | 2.57 (1.24–5.32) | 0.31 (0.19–0.49) |
| Sternoclavicular joint | 375 (5) | 64.4 (39.1–83.6) | 72.1 (48.3–87.8) | 4.68 (2.06–10.63) | 2.31 (1.33–4.02) | 0.49 (0.29–0.83) |
Hierarchical logistic regression modelling was used to determine summary estimates of the sensitivity, specificity, diagnostic odds ratio and likelihood ratios by the bivariate model approach. 95% CI 95% confidence interval, OR odds ratio, LR+ positive likelihood ratio, LR− negative likelihood ratio
aData either reported as shoulder or glenohumeral joint
bIn case of potential data overlap between studies, only data from one study was used according to criteria described in the “Methods” section