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. 2021 May 11;12:2683. doi: 10.1038/s41467-021-22993-5

Fig. 4. Replicative H2A and H2A.X replace H2A.W in h2a.w-2.

Fig. 4

a Locally weighted scatterplot smoothing (LOESS) fit of H2A.W, H2A.X, replicative H2A and H2A.Z levels averaged in 1 kb bins across chromosome 3 in WT and h2a.w-2. Average of two replicates shown. b Metaplots of average H2A.W, H2A.X, and replicative H2A levels from two replicates over H2A.W peaks in the chromosome arms and pericentromeres. c Smoothing spline fits (50 degrees of freedom) of changes in H2A.X and replicative H2A levels (h2a.w-2 minus WT; log2 ChIP/H3) in 1 kb windows plotted against WT H2A.W level. Source data underlying Fig. 4a are provided as a Source Data file.