Table 4.

Areas under the receiver operating characteristic curve for various prediction models in the Northwestern Medicine Enterprise Data Warehouse Heart Failure Cohort.

Model	N	AUROC
ATTRwt-CM RF model	39,654	0.80
ATTRwt-CM RF model, age > 70 years	23,570	0.82
Age only	39,624	0.54
Age + sex	39,618	0.62
Age + sex + ethnicitya	39,203	0.70
Age + sex + ethnicity + logBNPb	20,419	0.73
Age + sex + ethnicity + logBNP + abnormal troponin-Ic	15,046	0.73
ATTRwt-CM RF model + age + sex + ethnicity	39,203	0.83
ATTRwt-CM RF model + age + sex + ethnicity + total number of encounters	38,337	0.83

ATTRwt-CM amyloidogenic transthyretin (wild-type), AUROC area under the receiver operating characteristic curve, RF Random Forest, BNP B-type natriuretic peptide.

^aEthnicity categories: non-Hispanic White, non-Hispanic Black, Hispanic, Asian, others.

^bHighest BNP value in the electronic health record, log-transformed.

^cBased on the highest troponin-I in the electronic health record (abnormal defined as >0.04 ng/ml).