Fig. 7.

Characterization of NMDA receptor with agonists. DoD24 MCCs were used for Ca²⁺ imaging and were stimulated with different agonists of the NMDA receptor. a Percentage of cells reacting to HBSS, NMDA [50 µM], quinolinic acid [500 µM] (an endogenous NMDA-R agonist), domoic acid [1 µM] (a neurotoxin produced by algae, kainate- and AMPA-receptor agonist), or ibotenic acid [50 µM] (a fungal neurotoxin acting as NMDA-R agonist) compared to the whole cell population is shown. Data are means of three biological replicates ± SD. *p value < 0.05, ***p value < 0.001; b Averaged traces from Ca²⁺ signalling of a are shown. The full set of data with standard deviations is displayed in Fig. S6