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. 2020 Oct 23;48(5):1339–1350. doi: 10.1007/s00259-020-05057-6

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — In vitro autoradiography assays determining binding and IC₅₀ values of lutetium-177-labeled PSMA-617, PSMA-I&T, and nanobody JVZ-007. a Representative images of the autoradiography results on PC310 (PSMA-positive) and PC324 (PSMA-negative) PDX. b Quantification of the autoradiography results representing the total binding (percentage added activity (%AA)) of the radiotracers on PSMA-positive and PSMA-negative PDXs. c IC₅₀ curves of autoradiography displacement assays using the PC295 PDX. The error bars represent the standard deviation. Asterisks indicate significance (**P ≤ 0.01, ****P ≤ 0.0001)