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. 2020 Oct 23;48(5):1339–1350. doi: 10.1007/s00259-020-05057-6

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — Ex vivo DNA double-strand breaks analysis on PC295 PDX tissue. a Representative images of tumor sections of mice injected with [¹⁷⁷Lu]Lu-PSMA-617 or [¹⁷⁷Lu]Lu-PSMA-I&T at 4 h p.i. and non-treated animals (scale bar = 10 μm). b Corresponding 53BP1γH2AX foci analysis. Average number of foci per nucleus per mouse is depicted. c Corresponding γH2AX foci analysis. Average number of foci per nucleus per mice is depicted. All error bars indicate standard deviation