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. 2020 Nov 12;598(7879):144–150. doi: 10.1038/s41586-020-2907-3

Fig. 5. Phenotypic variability of individual t-types.

Fig. 5

a, Confusion matrix for classifying cells from each t-type into seven transcriptomic families using electrophysiological features. Only t-types with at least ten cells are shown. Values in each column sum to 1. Arrows mark t-types that are classified into wrong families more than 25% of the time. We used a kNN-based classifier with k = 10. b, Normalized total variance of features in each t-type. Higher values correspond to t-types with more variable phenotypes. Horizontal grey band, minimum to maximum normalized variances of k-means clusters. c, Three exemplary traces from Vip Mybpc1_2 cells (all with confidence ≥ 95%) and t-SNE overlay coloured by rebound. Inset, the same t-SNE embedding as in Fig. 1. Main plot, magnification. d, Three exemplary traces from Sst Pvalb Calb2 cells (confidence ≥ 95%) and t-SNE overlay coloured by maximum firing rate.