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. 2021 Apr 28;12:662839. doi: 10.3389/fneur.2021.662839

Table 4.

Comparisons of blood pressure relative to the MAPopt from wHVx during hypothermia.

Maximal MAP above MAPopt (n = 63) Maximal MAP below MAPopt (n = 63) AUC above MAPopt (n = 63) AUC below MAPopt (n = 63)
β P β P β P β P
Single-window wHVx
Paracentral gyri −0.147 0.044 −0.019 1.000 −0.003 1.000 −0.002 1.000
White matter −0.075 0.473 −0.004 1.000 −0.002 1.000 0.000 1.000
Basal ganglia −0.142 0.015 0.003 1.000 −0.005 0.446 0.002 1.000
Thalamus −0.149 0.013 −0.011 1.000 −0.005 0.439 0.001 1.000
Posterior limb of the internal capsule −0.064 1.000 0.010 1.000 −0.004 1.000 0.000 1.000
Brainstem −0.120 0.041 0.006 1.000 −0.004 1.000 0.002 1.000
Maximal MAP above MAPopt (n = 65) Maximal MAP below MAPopt (n = 65) AUC above MAPopt (n = 65) AUC below MAPopt (n = 65)
β P β P β P β P
Multi-window wHVx
Paracentral gyri −0.069 1.000 0.006 1.000 −0.004 1.000 0.001 1.000
White matter −0.037 1.000 0.004 1.000 −0.002 1.000 0.000 1.000
Basal ganglia −0.085 0.216 −0.012 1.000 −0.004 1.000 0.002 1.000
Thalamus −0.089 0.194 −0.021 1.000 −0.005 1.000 0.001 1.000
Posterior limb of the internal capsule −0.040 1.000 0.019 1.000 −0.003 1.000 0.001 1.000
Brainstem −0.089 0.139 −0.017 1.000 −0.003 1.000 0.001 1.000

Comparisons were adjusted for sex, partial pressure of arterial carbon dioxide, perinatal insult score, vasopressor use, and presence of electroencephalographic seizures. The analyses were also adjusted for multiple comparisons using Bonferroni corrections. Bold values are statistically significant p-values (p-values < 0.05).

MAP, mean arterial blood pressure; MAPopt, optimal mean arterial blood pressure; wHVx, wavelet hemoglobin volume index; AUC, area under the curve.