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. 2021 May 11;11:10036. doi: 10.1038/s41598-021-89494-9

Table 2.

Associations of TyG index, inflammatory markers and risk of metabolic syndrome incidence (odds rations and 95% confidence intervals).

Quartiles P for trend
Q1 Q2 Q3 Q4
TyG index
Range  ≤ 8.14 8.15–8.48 8.49–8.81  > 8.82
MS cases/total number of each quartile (%) 12/386 39/387 55/394 73/375
No adjusted 1 3.496 (1.799–6.780) 5.057 (2.662–9.604) 7.534 (4.016–14.132)  < 0.0001
Model 1 1 3.015 (1.542–5.896) 4.127 (2.146–7.936) 5.924 (3.113–11.275)  < 0.0001
Model 2 1 2.316 (1.169–4.588) 2.713 (1.389–5.300) 3.894 (2.011–7.537)  < 0.0001
Total leukocytes
Range  ≤ 5.30 5.31–6.12 6.13–7.03  > 7.04
MS cases/total number of each quartile (%) 32/389 43/384 45/385 59/384
No adjusted 1 1.407 (0.870–2.276) 1.477 (0.916–2.379) 2.025 (1.284–3.195) 0.021
Model 1 1 1.252 (0.769–2.038) 1.255 (0.773–2.037) 1.692 (1.064–2.689) 0.147
Model 2 1 1.187 (0.721–1.956) 1.102 (0.671–1.809) 1.298 (0.806–2.092) 0.730
Neutrophils
Range  ≤ 2.72 2.73–3.28 3.28—3.95  > 3.96
MS cases/total number of each quartile (%) 31/387 50/384 36/387 62/384
No adjusted 1 1.719 (1.072–2.757) 1.178 (0.713–1.946) 2.211 (1.400–3.491) 0.002
Model 1 1 1.707 (1.059–2.752) 1.044 (0.628–1.735) 2.090 (1.317–3.317) 0.002
Model 2 1 1.606 (0.985–2.618) 0.971 (0.579–1.630) 1.663 (1.034–2.672) 0.027
Lymphocytes
Range  ≤ 1.85 1.86–2.20 2.21–2.62  > 2.63
MS cases/total number of each quartile (%) 33/390 46/383 40/387 60/382
No adjusted 1 1.477 (0.922–2.366) 1.247 (0.769–2.023) 2.016 (1.284–3.164) 0.015
Model 1 1 1.378 (0.854–2.224) 1.066 (0.650–1.750) 1.663 (1.048–2.639) 0.089
Model 2 1 1.301 (0.796–2.126) 0.959 (0.578–1.592) 1.283 (0.797–2.064) 0.421
NLR
Range  ≤ 1.17 1.18–1.47 1.48–1.88  > 1.89
MS cases/total number of each quartile (%) 42/390 48/388 45/386 44/378
No adjusted 1 1.170 (0.753–1.817) 1.093 (0.700–1.708) 1.092 (0.697–1.710) 0.762
Model 1 1 1.155 (0.740–1.801) 1.102 (0.702–1.730) 1.186 (0.752–1.869) 0.888
Model 2 1 1.148 (0.728–1.810) 1.094 (0.689–1.736) 1.174 (0.736–1.873) 0.908

Data are expressed as ORs (95% CI). Model 1: adjusted for age, sex, smoking; model 2: Model 1 adjusted further for body mass index, blood pressure.