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. 2021 May 11;12:2670. doi: 10.1038/s41467-021-22958-8

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Scatterplots of each patient anti-spike neutralizing (a), S1 + S2 IgG (b), RDB IgG (c), S2 (d) IgG antibodies over time from symptoms onset. Antibody levels correspond to the reciprocal of the ID50 for nAbs or to arbitrary units for all other reactivities. Sampling during hospital attendance (ER or ward) or at post-discharge outpatient follow-up visits is shown by the indicated color code. The moving average of data + SE (black curve line + gray band), as obtained by a LOESS curve fitting polynomial regression, is displayed. Source data are provided as a Source Data file.