PV ablation affects the expression of genes involved in mitochondrial biogenesis and fusion
(A) Expression levels of PGC-1α, SIRT1, and VEGF in WT and PV−/− TA muscles.
(B) Expression levels of DRP1, FIS1, OPA1, MFN2, and MFN1 in WT and PV−/− TA muscles.
Data were normalized to WT and are presented as mean ± SEM. Expression levels were normalized to GAPDH. For statistical analysis, a parametric Student’s t test (two tailed, unpaired) was performed. ∗p < 0.05; ∗∗p < 0.01. See also Figure S5.