Table 2.

Cochrane Systematic Review and Meta-Analysis.¹⁹

Trial	Number of patients	Population	Corticosteroid regimen	Duration of therapy
Mikami et al24	31	Inpatient with CAP (non-ICU)	Prednisolone 40 mg IV daily	3 days
Meijvis et al13	304	Inpatient with CAP (non-ICU)	Dexamethasone 5 mg IV daily	4 days
McHardy et al25	126	Inpatient with CAP (any severity)	Prednisolone 20 mg PO daily	7 days
Hatakeyama et al26	30	Inpatient with CAP (any severity)	Methylprednisolone 20 mg daily	3 days
Snijders et al14	213	Inpatient with CAP (any severity)	Prednisolone 40 mg PO or IV daily	7 days
Blum et al11	785	Inpatient with CAP (any severity)	Prednisone 50 mg PO daily	7 days
Marik et al20	30	Inpatient with severe CAP	Hydrocortisone 10 mg/kg IV × 1 dose	1 dose
Confalonieri et al15	46	Inpatient with severe CAP	Hydrocortisone 200 mg IV bolus, then 10 mg/h	7 days
El-Ghamrawy et al21	34	Inpatient with severe CAP	Hydrocortisone 200 mg IV bolus, then 10 mg/h	7 days
Sabry et al22	80	Inpatient with severe CAP	Hydrocortisone 200 mg IV bolus, then 12.5 mg/h	7 days
Fernández-Serrano et al16	56	Inpatient with severe CAP	Methylprednisolone 200 mg IV bolus, then tapering infusion (3.3-0.8 mg/h)	9 days
Nafae et al23	80	Inpatient with severe CAP	Hydrocortisone 200 mg IV bolus, then 10 mg/h	7 days
Torres et al17	120	Inpatient with severe CAP	Methylprednisolone 0.5 mg/kg IV BID	5 days

Abbreviations: CAP, community-acquired pneumonia; ICU, intensive care unit; IV, intravenous; PO, by mouth; BID, twice daily.