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. 2021 Apr 28;12:671859. doi: 10.3389/fphar.2021.671859

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Copyright © 2021 De Martin, Gabbia, Folli, Bifari, Fiorina, Ferri, Stahl, Inturrisi, Pappagallo, Traversa and Manfredi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Changes in systolic (A) and diastolic (B) blood pressure 2 and 24 h after REL-1017 administration. The data represent differences from baseline in BP measurements taken during treatment. ***p < 0.001 and ****p < 0.0001 vs. placebo.