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. 2021 Apr 28;8:655157. doi: 10.3389/fmolb.2021.655157

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Copyright © 2021 Liu, Li, Bai and Xu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The expression of XIST and SIRT1 and autophagy are decreased, and the expression of miR-30d-5p is increased in the trigeminal sensory neurons of the diabetic mice. (A) The expression of XIST is measured by qPCR assays in the trigeminal sensory neurons of the diabetic mouse model. (B) The expression of miR-30d-5p is detected by qPCR assays in the trigeminal sensory neurons of the diabetic mouse model. (C) The expression of SIRT1 is examined by qPCR assays in the trigeminal sensory neurons of the diabetic mouse model. (D) The expression of LC3I, LC3II, and Beclin-1 is assessed by Western blot analysis in the trigeminal sensory neurons of the diabetic mouse model. N = 6, mean ± SD, **P < 0.01.