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. 2021 Apr 28;8:655157. doi: 10.3389/fmolb.2021.655157

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Copyright © 2021 Liu, Li, Bai and Xu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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XIST is able to sponge miR-30d-5p in the Schwann cells. (A) Bioinformatic analysis using ENCORI (http://starbase.sysu.edu.cn/index.php) shows the interaction of XIST with miR-30d-5p. (B,C) The RSC96 cells are treated with control mimic or miR-30d-5p mimic. (B) The expression of miR-30d-5p is detected by qPCR assays. (C) The luciferase activities of the wild-type XIST (WT) or mutant XIST (MUT) are detected by luciferase reporter gene assays. (D) The RSC96 cells are treated with control shRNA or XIST shRNA. The expression of miR-30d-5p is detected by qPCR assays. N = 3, mean ± SD, **P < 0.01.