Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Apr 28;9:645496. doi: 10.3389/fcell.2021.645496

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Bessy, Itkin and Passaro.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Bone marrow vascular structure. (A) Scheme of the organization of BM vasculature at different magnifications. The BM vasculature is highly interconnected with the tissue matrix, with small arterioles covered by pericytes entering the marrow from the bone and merging with the venous system via a network of sinusoidal capillaries. The vascularized marrow space is populated by hematopoietic and stromal cells embedded in a unique extracellular matrix. (B) Representative Z-stack two-photon microscopy image of vascular organization in the mouse calvarial bone marrow, with Nestin-GFP peri-arteriolar pericytes (green), TRITC-dextran labeled vascular lumen (red) and second harmonic generation (SHG) bone matrix (blue).