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. 2021 Apr 28;9:645496. doi: 10.3389/fcell.2021.645496

FIGURE 4.

FIGURE 4

Bioengineered vascularized BM niche unit. Schematic representation of the essential elements to be reproduced in an engineered vascularized BM niche-on-a-chip. These would include different matrix for bone and marrow space, as well as an intricate net of specialized vessels in close proximity with stromal and hematopoietic components.