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. 2021 Apr 28;12:609693. doi: 10.3389/fphar.2021.609693

FIGURE 8.

FIGURE 8

BBR alleviates ERS after CIRI. Berberine significantly inhibited CIRI induced up-regulation of CNPY2, GRP78 and CHOP, hallmarks of ERS. BBR, Berberine; CIRI, cerebral ischemia-reperfusion injury; CNPY2, canopy FGF signaling regulator 2; GRP78: glucose-regulated protein 78; CHOP: C/EBP homologous protein.