Table 1.

Antimycobacterial and cytotoxic activities of the lanostanes

	Antituberculosis	Cytotoxicity
Compound	M. tuberculosis H37Ra H37Ra	Vero cells
	MIC, μg ml−1	IC50, μg ml−1
1	0.391	18
8	3.13	15
9 (GA003)	0.0977	9.2
10	1.56	12
11	0.781	12
12	0.781	9.5
13	1.56	16
14	0.391	16
15	>50	18
16	0.781	15
17	0.781	8.7
18	>50	13
Rifampicina	0.025	–
Isoniazida	0.0469	–
Ellipticineb	–	1.3

^aStandard anti-TB drugs

^bStandard compound for the cytotoxicity assay