Table 1.
Baseline differences at the time of allocation in three-arms (n = 50 in each arm)
| Variables | SRP + MET + OHI | SRP + OHI | OHI + DT | p-value |
|---|---|---|---|---|
| Gender | ||||
|
Females Male |
20 30 |
23 27 |
25 25 |
0.600 |
| BMI status | ||||
|
Underweight Normal Overweight Obese |
2 15 25 8 |
0 15 28 7 |
3 14 27 6 |
0.770 |
| Smoking | ||||
|
No Yes |
47 2 |
46 2 |
43 4 |
0.559 |
| Diabetic management | ||||
|
Hypoglycemic Insulin Both |
37 4 9 |
31 9 10 |
38 6 6 |
0.427 |
| Co-morbidity | ||||
|
None Hypertension Others |
29 13 7 |
25 10 14 |
26 10 13 |
0.643 |
| Regular exercise | ||||
|
No Yes |
24 26 |
21 29 |
21 29 |
0.782 |
| Healthy diet | ||||
|
No Yes |
10 40 |
15 35 |
13 37 |
0.512 |
| HbA1c (cut-off 9%) | ||||
|
< 9% ≥ 9% |
25 25 |
29 21 |
29 21 |
0.649 |
| Mean age (years) | 52.72 ± 8.00 | 51.24 ± 8.27 | 52.82 ± 6.38 | 0.509 |
| Education (years) | 11.18 ± 4.97 | 10.69 ± 4.62 | 9.87 ± 5.52 | 0.540 |
| Mean BMI (m/kg2) | 26.66 ± 5.23 | 26.47 ± 3.61 | 25.72 ± 4.21 | 0.533 |
| Total teeth | 24.84 ± 3.15 | 24.88 ± 3.02 | 25.12 ± 3.27 | 0.891 |
| Teeth indicated for extraction | 0.97 ± 1.97 | 0.54 ± 1.11 | 1 ± 1.70 | 0.286 |
| HbA1c (%) | 9.11 ± 1.52 | 9.09 ± 1.75 | 8.88 ± 1.65 | 0.727 |
| BOP (%) | 26.03 ± 10.67 | 26.07 ± 9.57 | 26.25 ± 9.81 | 0.993 |
| PPD (mm) | 3.40 ± 0.88 | 3.56 ± 0.89 | 3.47 ± 0.86 | 0.644 |
| CAL (mm) | 3.94 ± 0.96 | 3.87 ± 1.04 | 3.80 ± 1.11 | 0.791 |
SRP, scaling root planning; MET, metronidazole; DT, delayed treatment; OHI, oral hygiene instructions; BOP, bleeding on probing; PPD, periodontal pocket depth; CAL, clinical attachment loss; mm, millimeter