Table 3.

Post intervention changes in periodontal and glycemic variables at different follow-up visits

Variables v/s intervention	On 1-month follow-up			On 3-months follow-up
Periodontal	Mean difference ∆	p-value*	p-value**	Mean difference ∆	p-value*	p-value**
Mean BOP %
∆ SRP + MET + OHI − DT + OHI	− 8.16	0.010	0.018	− 10.72	< 0.001	0.001
∆ SRP + OHI − DT + OHI	− 7.27		0.037	− 11.94		< 0.001
∆ SRP + MET + OHI − SRP + OHI	− 0.89		1.000	1.22		1.000
Mean PPD (mm)
∆ SRP + MET + OHI − DT + OHI	− 0.72	< 0.001	0.001	− 1.13	< 0.001	< 0.001
∆ SRP + OHI − DT + OHI	− 0.48		0.031	− 0.74		0.008
∆ SRP + MET + OHI − SRP + OHI	− 0.24		0.593	− 0.39		0.357
Mean CAL (mm)
∆ SRP + MET + OHI − DT + OHI	− 0.50	0.028	0.098	− 0.63	< 0.001	0.032
∆ SRP + OHI − DT + OHI	− 0.57		0.040	− 1.05		< 0.001
∆ SRP + MET + OHI − SRP + OHI	0.07		1.000	0.41		0.309
Glycemic	On 3-months follow-up			On 6-months follow-up
HbA1c (%)
∆ SRP + MET + OHI − DT + OHI	− 1.22	< 0.002	0.004	− 2.18	< 0.001	< 0.001
∆ SRP + OHI − DT + OHI	− 0.98		0.023	− 1.84		< 0.001
∆ SRP + MET + OHI − SRP + OHI	− 0.24		1.000	− 0.34		1.000
FBG (mg/dL)
∆ SRP + MET + OHI − DT + OHI	− 33.32	< 0.023	0.042	− 51.82	< 0.001	0.001
∆ SRP + OHI − DT + OHI	− 29.48		0.068	− 41.51		0.007
∆ SRP + MET + OHI − SRP + OHI	− 3.84		1.000	− 10.31		1.000

SRP, scaling root planning; MET, metronidazole; DT, delayed treatment; OHI, oral hygiene instructions

∆Between groups mean difference

*All Significant difference between three groups [p < 0.05] measured by One-way ANOVA have been made bold

**All Significant difference at p < 0.05 calculated through post-hoc bonferroni test have been made bold