TABLE 4.
Similarity-based prediction databases (information-based approach).
| Type | Brief introduction | URL | References |
| IBIS | IBIS is practical server that can sever and identify most of interaction (protein-protein, RNA-protein and etc.) | http://www.ncbi.nlm.nih.gov/Structure/ibis/ibis.cgi | Shoemaker et al., 2010 |
| PredUS | PredUS is a structural similarity-based method and it is useful for detection of several features including designing of adjacent protein, mapping the interfacial space residues, measurement of residue interface score | https://bhapp.c2b2.columbia.edu/PredUs/ | Zhang et al., 2011 |
| PrISEC | This server measures surface patch which its function algorithm based on surface residues and atomic formation. | http://prise.cs.iastate.edu/ | Jordan et al., 2012 |
| PS-HomPP* | Extracting of interfacial residues via similar residues between binding proteins(intelligent server) | http://ailab1.ist.psu.edu/PSHOMPPIv1.2/ | Esmaielbeiki and Nebel, 2014 |
| NPS-HomPPI* | Prediction of probable interacting residues with different proteins(unintelligent server) | http://ailab1.ist.psu.edu/NPSHOMPPI/ | Esmaielbeiki and Nebel, 2014 |
| ProBiS | Using local structure alignment for identification of protein-protein interfaces | http://probis.cmm.ki.si/ | Esmaielbeiki et al., 2016 |
* Intelligent server means a server that is considered protein with special connector. *Unintelligent server means a server that is considered protein with different connectors.