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. 2021 Apr 28;8:647095. doi: 10.3389/fmolb.2021.647095

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Copyright © 2021 Lu, Kong, Zhong, Hu and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Protein–protein interaction (PPI) network of (A) the top 20 positively and top 20 negatively correlated genes of each THBSs; (B) potential hub genes (node degree ≥10). Ellipses stand for positively correlated genes, triangles stand for negatively correlated genes, a larger size of the node stands for a larger absolute value of Spearman correlation coefficient, and a wider line stands for a larger combined score (LinkedOmics and Cytoscape).