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. 2021 Apr 28;11:643394. doi: 10.3389/fonc.2021.643394

Figure 2.

Figure 2

Manipulation of LINC00467 expression mediated migration, invasion and EMT of breast cancer cells. (A, B) Migratory and invasive capacities of LINC00467-depleted MCF-7 and MDA-MB-231 cells were assessed by Wound healing assay and Transwell assay, respectively. (C, D) Wound healing assay and Transwell assay were performed to assess migratory and invasive capacities of LINC00467-overexpressing MCF-7 and MDA-MB-231 cells. (E) Protein levels of EMT markers in MCF-7 and MDA-MB-231 cells with LINC00467 knockdown or overexpression were determined by Western blot. Images were taken at 100× magnification. Data are presented as mean ± S.D from three independent experiments. *P < 0.05; **P < 0.01. Student’s t-test.