Figure 6.

The higher E-cadherin expression in placentas from PE-like mice which indicated invasive abnormity of the trophoblast was inhibited by nicotine. Representative immunofluorescent images (A) and quantitative analysis (B) showed changes in the relative immunoreactivity of placental E-cadherin in all groups. The dotted frame represented the trophoblast layer stained by CK7 in the P and LPS+N group; the solid frame represented the degenerated trophoblast layer weakly stained by CK7. Scale bar=50 μm. ^**P < 0.01.