Table 2.

Detection of TDP-43 fragments in human neurological conditions

Disease	TDP-43 truncated forms	Reference
Amyotrophic lateral sclerosis	23-37 kDa fragments	(Neumann et al., 2006)
Frontotemporal lobar degeneration	23-27 kDa fragments	(Igaz et al., 2008)
Alzheimer's disease	TDP-25	(Rohn, 2008)
Corticobasal degeneration	TDP-25	(Uryu et al., 2008)
Pick disease	TDP-25 and TDP-35	(Rohn and Kokoulina, 2009)
Parkinson's disease	TDP-25 (in Lewy bodies)	(Kokoulina and Rohn, 2010)
Traumatic brain injury	35 kDa fragments	(Yang et al., 2014b)