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. 2021 May 12;16:32. doi: 10.1186/s13027-021-00375-2

Table 3.

Antibody titers’ fold changes (FC) in previously infected and not previously infected cohorts of healthcare providers to monitor vaccine immune responses

Analyzed cohorts Mean FC Min FC Max FC n (%)
PreViously infected subjects
 Post I / Pre 1.8 0.0 3.8 35 (100.0%)
NotPreviously infected subjects
 Post I / Pre 1.6 0.0 3.6 158 (100.0%)
 Post II / Post I 1.9 0.2 3.8 158 (100.0%)
 Post II / Pre 3.5 1.4 3.8 158 (100.0%)
 Post II/Pre x¯ ≤ 3.1 2.6 1.4 3.1 30 (19.0%)
 Post II/Pre 3.1< x¯ ≤ 3.3 3.2 3.1 3.3 12 (7.6%)
 Post II/Pre 3.3< x¯ ≤ 3.8 3.7 3.3 3.8 116 (73.4%)
 Post II/Pre = 3.8 3.8 72 (45.6%)

Previously infected subjects = subjects infected to SARS-CoV-2

Not previously infected subjects = subjects not infected to SARS-CoV-2

Pre = anti - SARS-CoV-2 S titers before the first dose

Post I = anti - SARS-CoV-2 S titers 20 days after the first dose

Post II = anti - SARS-CoV-2 S titers 8 days after the second dose

mean FC = mean fold changes of anti - SARS-CoV-2 S mean geometric titers

n (%) = number of subjects (percentage)