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. 2021 Apr 23;12:627738. doi: 10.3389/fphar.2021.627738

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Copyright © 2021 Duangjan, Rangsinth, Zhang, Wink and Tencomnao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cytotoxicity effect of AO extracts in neuronal (HT22 and Neuro-2a) cells. The effects of AO extracts on cell viability of HT22 (A) and Neuro-2a (B) cells. The effects of quercetin on cell viability of HT22 (C) and Neuro-2a (D) cells. Cells were treated with different concentrations of the extracts or compounds for 48 h following MTT assay. The results are expressed as the means ± SEM of independent experiments (n = 3); p ≤ 0.001 compared to the untreated control.