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. Author manuscript; available in PMC: 2022 Jun 1.
Published in final edited form as: Drug Alcohol Depend. 2021 Apr 20;223:108711. doi: 10.1016/j.drugalcdep.2021.108711

Table 2.

Multivariable Models of Transgender-related Discrimination and Substance Use Outcomes

OUTCOME 1: SUBSTANCE USE OUTCOME 2: SUBSTANCE USE DISORDER OUTCOME 3: SUBSTANCE USE TREATMENT






Bivariate Model 1 Bivariate Model 2 Bivariate Model 3






B 95% CI P aB 95% CI P OR 95% CI P aOR 95% CI P OR 95% CI P aOR 95% CI p
TGR
Discrimination
 Low 1.00 ---- ---- 1.00 ---- ---- 1.00 ---- ---- 1.00 ---- ---- 1.00 ---- ---- 1.00 ---- ----
 Low to moderate 0.26 −0.67–1.18 0.585 0.33 −0.60–1.26 0.49 1.17 0.73–3.98 0.22 1.50 0.60–3.73 0.38 1.43 0.60–3.41 0.43 1.59 0.61–4.10 0.34
 Moderate to high 0.66 −0.24–1.57 0.152 0.40 −0.57–1.36 0.42 2.44 1.11–5.37 0.02 2.12 0.87–5.14 0.09 2.15 0.97–4.80 0.06 2.49 1.01–6.20 0.05
 High 2.14 1.19–3.08 <0.0001 1.44 0.36–2.53 0.009 3.71 1.71–8.06 0.001 3.64 1.46–9.07 0.006 3.41 1.56–7.44 0.002 3.93 1.50–10.21 0.005
DEMOGRAPHICS
Age (in years) −0.03 −0.06–(−0.01) 0.042 −0.04 −0.07–(−0.01) 0.007 1.02 1.00–1.04 0.10 1.01 0.99–1.04 0.29 1.04 1.02–1.06 <0.0001 1.05 1.02–1.07 <0.0001
Gender Identity
 Trans feminine 1.00 ---- ---- 1.00 ---- ---- 1.00 ---- ---- 1.00 ---- ---- 1.00 ---- ---- 1.00 ---- ----
 Trans masculine −0.70 −1.41–0.01 0.05 −0.44 −1.19–0.32 0.26 0.44 0.26–0.74 0.002 0.50 0.28–0.89 0.02 0.46 0.27–0.78 0.004 0.87 0.47–1.62 0.66
Race
 White 1.00 ---- ---- 1.00 ---- ---- 1.00 ---- ---- 1.00 ---- ---- 1.00 ---- ---- 1.00 ---- ----
 Person of color 1.29 0.43–2.15 0.003 1.00 0.07–1.93 0.03 0.37 0.16–0.88 0.02 0.38 0.14–0.98 0.05 1.13 0.59–2.17 0.70 0.88 0.40–1.96 0.76
Survey Mode
 In-person 1.00 ---- ---- 1.00 ---- ---- 1.00 ---- ---- 1.00 ---- ---- 1.00 ---- ---- 1.00 ---- ----
 Online −3.55 −5.10–(−2.00) <0.0001 −3.17 −4.81–(−1.54) <0.0001 0.80 0.27–2.36 0.68 0.88 0.25–3.08 0.85 0.20 0.09–0.45 <0.0001 0.17 0.06–0.46 <0.00 01
VICTIMIZATION
Childhood Abuse
 No 1.00 ---- ---- 1.00 ---- ---- 1.00 ---- ---- 1.00 ---- ---- 1.00 ---- ---- 1.00 ---- ----
 Yes 1.06 0.37–1.75 0.003 0.63 −0.11–1.38 0.09 1.54 0.89–2.65 0.12 0.98 0.52–1.86 0.96 1.77 0.99–3.13 0.05 0.98 0.50-1.91 0.93
IPV - Lifetime
 No 1.00 ---- ---- 1.00 ---- ---- 1.00 ---- ---- 1.00 ---- ---- 1.00 ---- ---- 1.00 ---- ----
 Yes 1.93 1.20–2.67 <0.0001 1.58 0.81–2.36 <0.0001 3.83 2.26–6.48 <0.0001 3.05 1.70–5.48 <0.0001 2.27 1.33–3.87 0.003 1.46 0.79–2.70 0.22
Other Discrimination 0.04 −0.16–0.24 0.70 −0.41 −0.65–(−0.17) 0.001 0.94 0.80–1.10 0.45 0.92 0.77–1.11 0.39 1.04 0.89–1.21 0.63 0.98 0.82–1.18 0.88

B = Beta Coefficient; aB = Adjusted beta coefficient; aOR = Adjusted Odds Ratio; OR = Odds Ratio; TGR = Transgender-related; IPV = Intimate partner violence

Note. All models adjusted for age, gender identity, race, survey modality, and childhood physical and sexual abuse, and intimate partner violence. White connotes non-Hispanic white individuals. Childhood abuse includes physical or sexual abuse. Other reasons for discrimination include one or more of the following: age, HIV status, race, ethnicity, nationality, religion, sexual orientation, physical disability, education or income level, weight, and other aspect of your physical appearance.

Sample sizes: Model 1 = 530; Model 2 = 533; Model 3 = 528