Table II.
oHSV clinical trials for malignant glioma.
| oHSV | Country | Stage | Target disease | Delivery | Trial number |
|---|---|---|---|---|---|
| HSV1716 | UK | I | Recurrent high-grade glioma | Intratumoral/Peritumoral | NCT02031965 |
| G207 | US | I | Progressive and recurrent malignant glioma | Intratumoral injection | NCT00157703 |
| G47Δ | Japan | II | Recurrent or residual glioblastoma | Intratumoral injection | UMIN000015995 |
| rQNestin34.5 | US | I | Recurrent high-grade glioma | Peritumoral | NCT03152318 |
| C134 | US | I | Recurrent high-grade glioma | Intratumoral injection | NCT03657576 |
| M032 | US | I | Progressive and current high-grade glioma | Intratumoral injection | NCT02062827 |
oHSV, oncolytic herpes simplex virus.