Table 2.

The effect of HS and MOLP supplementation on the logfold change (logFC) of differentially expressed genes (DEGs) in pairwise comparison (HS vs. CON, HSM vs. CON and HSM vs. HS) that encode proteins in fat digestion and absorption pathway

Gene name	HS vs CON	P-value	HSM vs CON	P-value	HSM vs. HS	P-value	Predicted function
APOA4	15.69	< 0.0001	16.48	< 0.0001			Apolipoprotein A-IV precursor
APOA1	4.36	< 0.0001	5.01				Apolipoprotein A-I preproprotein
FABP1	13.49	< 0.0001	14.14	< 0.0001			Fatty acid-binding protein, liver
FABP2	2.62	< 0.0001	5.01	< 0.0001	2.39	< 0.0001	Fatty acid-binding protein, intestinal
MTTP	1.29	< 0.0001	1.32	< 0.0001			Microsomal triglyceride transfer protein large subunit
LOC100344166	8.89	< 0.0001	9.97	< 0.0001			Phospholipase A2, membrane associated-like
LOC100339512	−1.71	0.006	−2.69	< 0.0001			Pancreatic triacylglycerol lipase-like
LOC100343913	1.84	< 0.0001			−1.28	< 0.0001	Phospholipase A2, membrane-associated
PLA2G2F	−11.75	0.015	−11.75	0.015			Group IIF secretory phospholipase A2
PLA2G12B	2.06	0.012			1.35	0.016	Group XIIB secretory phospholipase A2-like protein isoform X2
PLA2G5			−1.83	< 0.0001			Calcium-dependent phospholipase A2
NPC1L1			12.80	< 0.0001	5.81	< 0.0001	Niemann-Pick C1-like protein 1 precursor
APOB			1.04	< 0.0001			Apolipoprotein B
ABCG8			9.84	0.015	9.84	0.008	ATP-binding cassette sub-family G member 8 isoform X2
LOC100359181			−2.51	< 0.0001	−1.45	< 0.0001	2-acylglycerol O-acyltransferase 2-B
PLA2G1B					1.60	< 0.0001	Phospholipase A2

It may be noted that in pairwise comparison, first group (e.g. in HS vs. CON comparison, the HS group) represents the up- or down-regulated DEGs as compared to other group when logFC value is positive or negative respectively