Table 1.
Baseline clinical characteristics of the study population
| Variables | Normal geometry (n = 7939) | Concentric remodeling (n = 759) | Concentric hypertrophy (n = 426) | Eccentric hypertrophy (n = 816) | Ptrend |
|---|---|---|---|---|---|
| Age, years | 52.49 ± 10.07 | 57.99 ± 10.95 | 60.79 ± 9.90 | 59.22 ± 10.05 | < 0.001 |
| Male, n (%) | 3817 (48.1) | 329 (43.3) | 175 (41.1) | 269 (33.0) | < 0.001 |
| BSA, m2 | 1.66 ± 0.17 | 1.61 ± 0.19 | 1.64 ± 0.19 | 1.60 ± 0.18 | < 0.001 |
| BMI, kg/m2 | 24.71 ± 3.62 | 24.80 ± 3.91 | 25.86 ± 4.04 | 25.36 ± 3.90 | < 0.001 |
| Smoking, n (%) | 2871 (36.2) | 259 (34.1) | 147 (34.5) | 243 (29.8) | < 0.01 |
| Drinking, n (%) | 1887 (23.8) | 159 (20.9) | 90 (21.1) | 115 (14.1) | < 0.001 |
| Heart rate, bpm | 77.90 ± 12.94 | 82.02 ± 14.64 | 80.65 ± 14.59 | 77.91 ± 13.34 | < 0.001 |
| SBP, mmHg | 138.50 ± 20.94 | 150.18 ± 25.62 | 170.11 ± 26.50 | 154.55 ± 25.74 | < 0.001 |
| DBP, mmHg | 80.93 ± 10.87 | 85.37 ± 12.95 | 92.61 ± 14.63 | 85.26 ± 13.34 | < 0.001 |
| Hypertension, n (%) | 3502 (44.1) | 504 (66.4) | 395 (92.7) | 599 (73.4) | < 0.001 |
| Medication for hypertension, n (%) | 847 (10.7) | 195 (25.7) | 202 (47.4) | 227 (27.8) | < 0.001 |
| History of CVD, n (%) | 492 (6.2) | 99 (13.0) | 89 (20.9) | 118 (14.5) | < 0.001 |
| TC, mmol/L | 5.20 ± 1.06 | 5.43 ± 1.14 | 5.65 ± 1.27 | 5.41 ± 1.15 | < 0.001 |
| TG, mmol/L | 1.56 ± 1.46 | 1.74 ± 1.30 | 1.89 ± 1.41 | 1.66 ± 1.34 | < 0.001 |
| LDL-C, mmol/L | 2.91 ± 0.81 | 3.11 ± 0.91 | 3.27 ± 0.92 | 3.04 ± 0.88 | < 0.001 |
| HDL-C, mmol/L | 1.42 ± 0.39 | 1.45 ± 0.43 | 1.39 ± 0.38 | 1.39 ± 0.35 | < 0.01 |
| Dyslipidemia, n (%) | 2740 (34.5) | 338 (44.5) | 201 (47.2) | 326 (40.0) | < 0.001 |
| Estimated GFR, mL/min/1.73 m2 | 94.82 ± 15.02 | 89.48 ± 15.24 | 85.58 ± 18.50 | 87.68 ± 15.84 | < 0.001 |
| FPG, mmol/L | 5.82 ± 1.48 | 6.23 ± 2.34 | 6.24 ± 1.79 | 6.11 ± 1.85 | < 0.001 |
| Diabetes, n (%) | 712 (9.0) | 113 (14.9) | 91 (21.4) | 131 (16.1) | < 0.001 |
| Medication for diabetes, n (%) | 245 (3.1) | 48 (6.3) | 24 (5.6) | 52 (6.4) | < 0.001 |
BSA body surface area, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, CVD cardiovascular disease, TC total cholesterol, TG triglyceride, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, GFR glomerular filtration rate, FPG fasting plasma glucose