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. Author manuscript; available in PMC: 2021 May 12.
Published in final edited form as: Mol Pharm. 2020 Jul 22;17(8):2849–2863. doi: 10.1021/acs.molpharmaceut.0c00247

Figure 3.

Figure 3.

In vitro monolayer studies on cell viability. (A) Viability of BxPC-3 cells in monolayer cultures under normoxic and hypoxic (2% O2) conditions. Control treatments lack encapsulated drugs (n = 8). (B) Cellular uptake after 2 hours of iRGD conjugated hypoxia-responsive polymersomes in monolayer cultures of BxPC-3 cells. Control represents polymersomes without iRGD. (C) Cellular uptake using a FITC conjugated polymer and flow cytometry, showing fold increase in cellular uptake at selected time points (n = 3). * p-value <0.05.