Table 2.
Markers of the phases of the cell cycle
| Phase | Marker | Compartment |
|---|---|---|
| early G1 | CCND1:CDK6(P@Thr):CDKN1B | Nucleoplasm |
| pRB:E2F1:DP1:SWI:SNF:HDAC1 | Nucleoplasm | |
| SWI:SNF:HDAC1:SUV39H1:pRB:E2F1:DP1 | Nucleoplasm | |
| CCND1:CDK4(P@Thr172):CDKN1B | Nucleoplasm | |
| pRB:E2F1:DP1:SWI:SNF:HDAC1:SUV39H1:HP1gamma | Nucleoplasm | |
| late G1 | pRB(P):E2F1:DP1:SWI:SNF:HDAC1 | Nucleoplasm |
| pRB(P|P):E2F1:DP1:SWI:SNF | Nucleoplasm | |
| early S | CCNE1:CDK2(P@Thr160) | Nucleoplasm |
| late S | CCNA2:CDK2(P@Thr160) | Nucleoplasm |
| G2 | CCNB1:CDK1(P@Tyr15) | Cytoplasm |
| CCNB1:CDK1(P@Tyr15|P@Thr14) | Cytoplasm | |
| CCNB1:CDK1 | Cytoplasm | |
| CCNB1:CDK1(P@Thr14) | Cytoplasm | |
| M | CDC25(P) | Nucleoplasm |
| WEE1(P@Ser53) | Nucleoplasm | |
| CCNB1:CDK1(P@Thr161) | Nucleoplasm | |
| CDC20(P) | Nucleoplasm |
The markers for each phase of the cell cycle are given under a textual form. The names used to describe the markers are the labels of the corresponding entities in the map. Subunits in complexes are separated using the “:” character. Text in parantheses gives the post-translational modifications of a given entity (protein or complex subunit). For example, “P@Thr172” represents a phosphorylation at threonine 172. A same entity may have more than one post-translational modifications, separated in the text by the “|” character