Figure 3. MS IgG Binds a Diverse Repertoire of Commensals.

(A) Sorting strategy of IgG⁺IgA⁺ and IgG⁺IgA⁻-coated bacteria in 5 patients with RR-MS. Composition of sorted fractions was next analyzed by using 16S rRNA sequencing. (B) Genera diversity in IgG⁺IgA⁺ and IgG⁺IgA⁻-sorted fractions calculated by using the Shannon index. (C) Median relative abundance of the 30 most frequent genera in sorted fractions from 1 representative RR-MS patient. MS = multiple sclerosis; RR = relapsing-remitting.