Table 1.
Required measurements | Before registration | During protocol treatment | Discontinuation of protocol treatment | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Chemotherapy | Surgery | ||||||||||||
Course | 1 | 2 | If chemotherapy is continued | Before surgery | During surgery | 28 days after surgery | |||||||
Day | 1 | 8 | 15 | 29 | 36 | 43 | |||||||
Patient characteristics | ○ | ||||||||||||
Performance status | ○ | ○ | ○ | ○ | ○ | ○ | ○ | ○ | ○ | ||||
Symptoms | ○ | ○ | ○ | ○ | ○ | ○ | ○ | ○ | ○ | ||||
Blood count | ○ | ○ | ○ | ○ | ○ | ○ | ○ | ○ | ○ | ||||
Blood biochemistry | ○ | ○ | ○ | ○ | ○ | ○ | ○ | ○ | ○ | ||||
CEA, CA19-9 | ○ | ○ | ○ | ||||||||||
ECG | ○ | ||||||||||||
QOL assessment | ○ | ○ | ○ | ○ | |||||||||
Contrast CT scan | ○ | ○ | ○ | ||||||||||
Administration record | |||||||||||||
Gemcitabine | ○ | ○ | ○ | ○ | ○ | ○ | ○ | ||||||
Nab-paclitaxel | ○ | ○ | ○ | ○ | ○ | ○ | ○ | ||||||
Adverse events | ○ | ○ | ○ | ○ | ○ | ○ | ○ | ||||||
Operative findings | ○ | ||||||||||||
Postoperative complications | ○ | ||||||||||||
Pathological findings | ○ | ||||||||||||
CEA, carcinoembryonic antigen; CA19-9, carbohydrate antigen 19-9; ECG, electrocardiogram; QOL, quality of life; CT, computed tomography.