Table 1.
Baseline characteristics of the study population.
| Characteristics | Non EMI patients | EMI patients | p |
|---|---|---|---|
| N (%) | 308 (89) | 38 (11) | |
| Median age (range) | 65 (17–89) | 62 (26–81) | Ns |
| Male/female | 164/144 | 22/16 | Ns |
| Laboratory values, median (range) | |||
| Hemoglobin, g/dl | 9 (3–15.5) | 10 (6–14.8) | 0.002 |
| Platelets, x 109/l | 64 (3–590) | 61 (5–323) | Ns |
| White blood cells, 109/l | 11.3 (0.7–400) | 11.5 (1.3–272) | Ns |
| LDH, IU/l | 400 (106–7565) | 467 (124–3459) | Ns |
| Percent bone marrow blasrs, mean (SD) | 33.4 (31.7) | 34.3 (27.14) | Ns |
| Morphology (%) | |||
| Monocytoid | 50 (16) | 25 (66) | |
| Other morphologies | 258 (84) | 13 (34) | |
| Molecular biology (%) | |||
| NPM1+ | 32 (10) | 5 (13) | Ns |
| FLT3+ | 46 (18) | 7 (20) | Ns |
| Karyotype (%) | |||
| Normal karyotype | 111 (61) | 16 (62) | Ns |
| Trysomy 8 | 12 (6) | 6 (23) | 0.02 |
| Inversion (16) | 11 (5) | 2 (7) | Ns |
| 11q23 abnormalities | 7 (3) | 6 (18) | 0.001 |
| t(8;21) | 7 (3) | 1 (3) | Ns |
| Hct (%) | |||
| Yes | 81 (26) | 13 (44) | Ns |
| No | 223 (71) | 25 (66) | |