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. 2020 Aug 27;42(5):726–734. doi: 10.1038/s41401-020-00502-6

Fig. 1. RUS ameliorated PM-induced pulmonary pathological damage in mice.

Fig. 1

Mice were orally administered RUS (0.1, 0.3, 1 mg/kg) or DEX (1 mg/kg) prior to intratracheal PM (50 mg/kg) injection, and lung tissues were collected at 24 h after PM challenge. a The gross morphology of the mouse lung was observed and recorded. b The lung wet/dry ratio was determined (n = 6 lung tissue samples from six mice). c Histopathological changes in the lung were measured by H&E staining (scale bar = 100 μm). d Lung pathological injury scores were calculated (n = 3 lung tissue samples from three mice). Data are shown as the means ± SDs. ##P < 0.01 compared with the sham group; **P < 0.01 compared with the model group.