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. 2021 May 12;11:10056. doi: 10.1038/s41598-021-89401-2

Table 1.

Participants' characteristics and dyslipidemia status.

Variables Total N (%) Dyslipidemia N (%) Normal N (%) *p-value
Total 135,403 57,760 (42.7) 77,642 (57.3)
Age (years) 56.6 ± 9.9 56.5 ± 9.7 56.6 ± 10.2 0.120
Median (IQR)
40–49 35,617 (26.3) 14,821 (25.7) 20,796 (26.8) < 0.001
50–59 57,300 (42.3) 25,037 (43.3) 32,263 (41.6)
60–69 26,154 (19.3) 11,437 (19.8) 14,717 (19.0)
70 and above 16,331 (12.1) 6465 (11.2) 9866 (12.7)
Sex
Men 66,259 (48.9) 27,816 (48.2) 38,443 (49.5) < 0.001
Women 69,144 (51.1) 29,945 (51.8) 39,199 (50.5)
Residence
Rural 72,556 (53.6) 31,292 (54.2) 41,264 (53.1) < 0.001
Urban 62,847 (46.4) 26,469 (45.8) 36,378 (46.9)
Nationality
Han 130,934 (96.7) 55,557 (96.2) 75,377 (97.1) < 0.001
Others 4465 (3.3) 22.3 (3.8) 2262 (2.9)
Marital status
Married 80,154 (59.2) 32,362 (56.0) 47,792 (61.6) < 0.001
Unmarried 55,248 (40.8) 25,398 (44.0) 29,850 (38.4)
Level of education
Primary and below 84,118 (62.1) 37,459 (64.9) 46,659 (60.1) < 0.001
Junior/Middle School 32,233 (23.8) 12,264 (21.2) 19,969 (25.7)
Senior High School 13,104 (9.7) 5598 (9.7) 7506 (9.7)
College and above 5948 (4.4) 2440 (4.2) 3508 (4.5)
Geographical regions
North 75,174 (55.5) 29,172 (50.5) 46,002 (59.2) < 0.001
South 60,229 (44.5) 28,589 (49.5) 31,640 (40.8)
Stroke belt zone
Yes 23,262 (17.2) 9449 (16.4) 13,813 (17.8) < 0.001
No 112,142 (82.8) 48,312 (83.6) 63,830 (82.2)
Weight 65.0 (58.0–71.5) 65.0 (58.0–72.0) 55.0 (49.0–63.0) < 0.001
Height 162.1 ± 8.4 161.9 ± 8.6 162.2 ± 8.3 < 0.001
BMI
Median (IQR) 25.2 (23.0–27.5) 25.7 (23.5–27.9) 25.1 (22.7–27.1) < 0.001
Underweight (< 18.5 kg/m2) 46,598 (34.4) 16,968 (29.4) 29,630 (38.2) < 0.001
Normal (≥ 18.5 to < 24.0 kg/m2) 1835 (1.4) 568 (1.0) 1267 (1.6)
Overweight (≥ 24.0 to < 28 kg/m2) 59,314 (43.8) 26,232 (45.4) 33,082 (42.6)
Obesity (≥ 28.0 kg/m2) 27,655 (20.4 13,992 (24.2) 13,663 (17.6)
Waist circumference
Median (IQR) 86.0 (80.0–93.0) 88.0 (80.0–95.0) 85.0 (79.0–92.0) < 0.001
Normal ≤ 90/80 cm (M/W) 56,214 (42.0) 21,034 (36.7) 35,180 (45.9) < 0.001
Central obese ˃ 90/80 cm (M/W) 77,700 (58.0) 36,230 (63.3) 41,470 (54.1) < 0.001
Family history of dyslipidemia 127,624 (94.3) 53,695 (93.0) 3714 (4.8) < 0.001
Drinking (current) 25,747 (19.0) 11,249 (19.5) 14,498 (18.7) < 0.001
Smoking (current) 43,992 (32.5) 19,078 (33.0) 24,914 (32.1) < 0.001
Physical activity 83,913 (62.0) 35,349 (61.2) 48,564 (62.5) < 0.001
Blood lipids (mmol/l), median (IQR)
TC 4.9 (4.2–5.6) 5.3(4.4–6.3) 4.7 (4.2–5.3) < 0.001
HDL-C 1.3 (1.1–1.6) 1.1 (0.9–1.4) 1.4 (1.2–1.7) < 0.001
LDL-C 2.9(2.2–3.4) 3.0 (2.2–3.9) 2.8 (2.2–3.2) < 0.001
TG 1.5 (1.1–2.2) 2.3 (1.5–3.1) 5.5 (5.0–6.2) < 0.001
Non-HDL-C 3.5 (2.8–4.2) 4.1 (3.3–4.9) 3.2 (2.6–3.8) < 0.001

Dyslipidemia was defined as total cholesterol (TC) > 6.22 mmol/L or low-density lipoprotein (LDL-C) > 4.14 mmol/L or high-density lipoprotein (HDL-C) < 1.04 mmol/L or triglycerides (TG) > 2.26 mmol/L or non-high density lipoprotein > 4.9 mmol/L or self-reported treatment. Data shown as mean ± SD, or median (IQR) or n (%). *p-value for comparison of dyslipidemia vs. normal subjects. Men (M), Women (W). Unmarried (widowed/divorced/others).