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. 2020 Jul 21;42(4):573–584. doi: 10.1038/s41401-020-0473-8

Fig. 3. Matrine regulated the proliferation, migration, and transdifferentiation of cardiac fibroblasts via p38 in vitro.

Fig. 3

a The mRNA levels of Col1 and Col3 in neonatal rat cardiac fibroblasts among groups (n = 6). b Immunofluorescence staining of α-SMA and statistical results in neonatal rat cardiac fibroblasts (n = 6). c Representative images of the wound scratch assay at 0 and 12 h (n = 4). d Cell proliferation as detected with a bromodeoxyuridine (BrdU) cell proliferation ELISA kit. e, f Representative Western blots and quantitative results (n = 6). g The relative mRNA levels of Col1, Col3, Ctgf, and α-Sma (n = 6). h Representative images of Western blots and the quantitative data (n = 6). Values represent the means ± SEM. *P < 0.05 versus PBS + vehicle, #P < 0.05 versus TGF-β + vehicle. d *P < 0.05 versus 1% FBS + vehicle, #P < 0.05 versus 10% FBS + vehicle. g, h *P < 0.05 versus the matched group, NS indicates no significance.