Skip to main content
. 2020 Aug 7;42(5):735–743. doi: 10.1038/s41401-020-0493-4

Fig. 3. CypD is involved in the effect of berberine on insulin resistance.

Fig. 3

a Animal study protocol. Mice were divided into three Ppif+/+ (wild-type) groups and three Ppif−/− (CypD deficiency) groups, and each group received saline or intralipid i.v. administration with or without BBR i.g. administration 60 min before the insulin tolerance test (ITT). b Immunoblotting analysis of CypD protein expression in the skeletal muscle of Ppif+/+ and Ppif−/− mice normalized to GAPDH. The data are shown as the mean ± SD. ###P < 0.0001 vs. Ppif−/−. c ITT and d Kitt. The data are shown as the mean ± SD. **P < 0.01 vs. Ppif+/+-saline group, #P < 0.05 vs. Ppif+/+-intralipid group; ns not significant; n = 4.